| Case Study: Sensor Prototyping | | Business Challenge: | | BEST-Bio was approached by a client who required 20 prototype continuous glucose monitoring (CGM)
sensors for an animal test. The specifications were: | | | The total length between the sensor end and the connections was to be 12 inches,
with a diameter of 1/16 inch or less throughout the length | | The sensors must be able to withstand immersion in liquid for several weeks without
loss of performance | BEST-Bio Solution: | | To meet these requirements, BEST-Bio modified an existing CGM sensor with precision soldering of 30 AWG
wires to extend the length of the sensor by 12 inches. The solder points were potted with marine-grade adhesive to render them waterproof, and then the
encapsulated solder points were sealed with biocompatible heat-shrink tubing. | | The modified sensors were subjected to extended soak tests to verify
their operation while submerged in liquid. The graphs to the right show the response of the sensor to step changes in glucose concentration while fully immersed
in the test solution. | | BEST-Bio was able to deliver these modified sensors to the client on an extremely fast timescale, allowing the client to
rapidly enter into animal testing of their glucose monitoring technology. | | |
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