BEST-Biotech
Finite Element Modeling
BEST-Bio's consultancy specializes in Finite Element Modeling and its application to biosensor and medical diagnostics design and troubleshooting.
BEST-Bio is unique in that we can both build Finite Element Models to predict and understand sensor behavior, and we can also validate the model using real-world data gathered at our San Jose sensor and medical diagnostic laboratory. By going through an iteration of model building, data collection, and model refinement based on real world data, we can develop a robust model of the sensor.
A well-designed model of a biosensor or a medical diagnostic can help at every stage of a product's life cycle, whether in the early development phase or for understanding the sensor if subsequent manufacturing issues arise and the sensors moves out of specification.
A medical diagnostic sensor often has several elements which contribute to the output signal including:
  • Microfluidic flow characteristics
  • Dissolution of active materials (enzymes, antibodies, DNA, RNA, etc.)
  • Biochemical reactions and chemical reactions
  • Electron transfer characteristics at the electrode
  • Construction of a comprehensive model of a medial diagnostic therefore requires an understanding of many physics and chemistry fundamentals including Navier-Stokes, Fick's laws, Michaelis-Menten kinetics, the Nernst Equation, the Bulter-Volmer equation, etc.
    BEST-Bio's team of Ph.D. scientists and engineers have a proven track record of delivering against our customers' biosensor and medidal diagnostics programs.
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